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Merck
CN

SAB5702374

Anti-RPA70/RPA1 Antibody, clone 5R7S3, Rabbit Monoclonal

Synonym(s):

HSSB, MST075, REPA1, RF-A, RP-A, RPA70

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5R7S3, monoclonal
Application:
ChIP, IP, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

5R7S3, monoclonal

form

liquid

mol wt

70 kDa

species reactivity

human, rat

concentration

0.55 mg/mL

technique(s)

ChIP: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MVGQLSEGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDGLNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMELE

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RPA1(6117)

General description

As part of the heterotrimeric replication protein A complex (RPA/RP-A, binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RPA70/RPA1 (P27694).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IP, ChIP


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

常规特殊物品

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Global Trade Item Number

SKUGTIN
SAB5702374-100UL04065270695208