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Key Documents

SAB5702412

Sigma-Aldrich

Anti-Prolyl hydroxylase PHD1 (EGLN2) Antibody, clone 2G9M7, Rabbit Monoclonal

Synonym(s):

EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.21

biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

2G9M7, monoclonal

form

liquid

mol wt

44 kDa

species reactivity

rat, human, rat

concentration

0.18 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALV

UniProt accession no.

Q96KS0

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EGLN2(112398)

General description

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Prolyl hydroxylase PHD1 (EGLN2) (Q96KS0).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

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