SAB5702463
Anti-TTR Antibody, clone 5H4L7, Rabbit Monoclonal
Synonym(s):
CTS, CTS1, HEL111, HsT2651, PALB, TBPA
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
material
colorless
biological source
rabbit
conjugate
unconjugated
clone
5H4L7, monoclonal
form
liquid
species reactivity
mouse, mouse
concentration
0.50 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
KTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TTR(7276)
Application
WB
General description
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 68-147 of human TTR (P02766).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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