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Safety Information

SAB5702465

Sigma-Aldrich

[KO Validated]Anti-CDK2 Antibody, clone 10E0N5, Rabbit Monoclonal

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Synonym(s):
CDKN2, p33(CDK2)

biological source

rabbit

Quality Level

100

material

colorless

clone

10E0N5, monoclonal

form

liquid

species reactivity

rat, human, rat

concentration

1.6 mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

RRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

UniProt accession no.

P24941

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDK2(1017)

General description

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 199-298 of human CDK2 (P24941).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Regulatory Information

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