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CDK2

cyclin-dependent kinase 2

别名:
p33(CDK2)
物种:
UniProtKB ID:
基因ID:
  • Human(1017) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(12566) cyclin-dependent kinase 2
  • Rat(362817) cyclin dependent kinase 2
  • domestic guinea pig(100714324) cyclin-dependent kinase 2
  • Zebrafish(406715) cyclin-dependent kinase 2
  • chicken(100529062) cyclin-dependent kinase 2
  • naked mole-rat(101725353) cyclin-dependent kinase 2
  • dog(606931) cyclin-dependent kinase 2
  • domestic cat(101093368) cyclin-dependent kinase 2
  • sheep(100216433) cyclin-dependent kinase 2
  • Domestic Rabbit(100134865) cyclin-dependent kinase 2
  • cow(519217) cyclin-dependent kinase 2
  • Goat(100860751) cyclin-dependent kinase 2

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Antibodies

货号
说明
物种反应性
应用
Anti-Phospho-CDK2-T160 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
[KO Validated]Anti-CDK2 Antibody, clone 10E0N5, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot
Anti-CDK1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Monoclonal Anti-CDK2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL7990, purified immunoglobulin, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Rabbit anti-CDK2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human, mouse
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

货号
说明
物种
酪磷蛋白23, ≥98%,
物种
human
NU2058, >98% (HPLC),
物种
human
白皮杉醇, powder,
物种
human
6-O-甲基鸟嘌呤, 97%,
物种
human
Tyrphostin 51, ≥98%,
物种
human

Proteins

货号
说明
物种
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
物种
human
CDK2/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
CDK2/CyclinE1,活性,GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cdk2,
物种
mouse
MISSION® esiRNA, targeting human CDK2,
物种
human