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Merck
CN

SAB5702509

Anti-PAR2 Antibody, clone 9X8E6, Rabbit Monoclonal

Synonym(s):

GPR11, PAR2

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
IHC, WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

material

colorless

clone

9X8E6, monoclonal

form

liquid

mol wt

55 kDa

species reactivity

rat, human

concentration

0.38 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

ICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... F2RL1(2150)

General description

This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 298-397 of human PAR2 (P55085).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC


Storage Class

10 - Combustible liquids

wgk

WGK 1



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