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Merck
CN

SAB5702510

Anti-Galactosidase alpha (GLA) Antibody, clone 7G8T9, Rabbit Monoclonal

Synonym(s):

GALA

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

material

colorless

clone

7G8T9, monoclonal

form

liquid

mol wt

50 kDa

species reactivity

human, rat

concentration

1.23mg/mL

technique(s)

western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

FMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFG

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GLA(2717)

General description

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Galactosidase alpha (GLA) (GLA) (P06280).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB


Storage Class

10 - Combustible liquids

wgk

WGK 1



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