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SAB5702557

Anti-CBX4 Antibody, clone 1R5G6, Rabbit Monoclonal

Synonym(s):

NBP16, PC2

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
IP, WB
Citations:
-
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biological source

rabbit

Quality Segment

100

conjugate

unconjugated

material

colorless

clone

1R5G6, monoclonal

form

liquid

mol wt

60 kDa

species reactivity

human, rat

concentration

0.35 mg/mL

technique(s)

immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

EVILLDSDLDEPIDLRCVKTRSEAGEPPSSLQVKPETPASAAVAVAAAAAPTTTAEKPPAEAQDEPAESLSEFKPFFGNIIITDVTANCLTVTFKEYVTV

UniProt accession no.

O00257

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CBX4(8535)

General description

E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 461-560 of human CBX4 (O00257).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IP

Storage Class

10 - Combustible liquids

wgk

WGK 1

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