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Merck
CN

SAB5702595

Anti-CDC23 Antibody, clone 1Q2I3, Rabbit Monoclonal

Synonym(s):

ANAPC8, APC8, CUT23

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
IF, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

1Q2I3, monoclonal

form

liquid

mol wt

69 kDa

species reactivity

human, rat

concentration

1.55 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

YSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQGETPTTEVPAPFFLPASLSANNTPTRRVSPLNLSSVTP

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDC23(8697)

General description

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 498-597 of human CDC23 (Q9UJX2).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB5702595-100UL04065270692023