SAB5702601
Anti-CAD Antibody, clone 0O8D6, Rabbit Monoclonal
Synonym(s):
CDG1Z, EIEE50, GATD4
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
0O8D6, monoclonal
Application:
IF, IHC, WB
Citations:
-
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
0O8D6, monoclonal
form
liquid
mol wt
250 kDa
Quality Level
Gene Information
human ... CAD(790)
concentration
1.50 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSA
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAD (P27708).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC, IF/ICC
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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