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Merck
CN

SAB5702601

Anti-CAD Antibody, clone 0O8D6, Rabbit Monoclonal

别名:

CDG1Z, EIEE50, GATD4

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关于此项目

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
mouse
Technique(s):
immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000
Application:
IF, IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

0O8D6, monoclonal

form

liquid

mol wt

250 kDa

species reactivity

mouse

concentration

1.50 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDEMDEFGLCKWFESSGIHVAALVVGECCPTPSHWSA

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CAD(790)

General description

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAD (P27708).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC


存储类别

10 - Combustible liquids

wgk

WGK 1

法规信息

常规特殊物品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
SAB5702601-100UL04065270692085