SAB5702618
Anti-ACTN2 Antibody
rabbit monoclonal, 2P7E6
Synonym(s):
CMD1AA, CMH23
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
Species reactivity:
rat, human
Clone:
2P7E6, monoclonal
Application:
IF, WB
Citations:
-
Product Name
Anti-ACTN2 Antibody, clone 2P7E6, Rabbit Monoclonal,
biological source
rabbit
Quality Segment
material
colorless
clone
2P7E6, monoclonal
form
liquid
mol wt
104 kDa
species reactivity
rat, human
concentration
0.34 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MNQIEPGVQYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANV
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ACTN2(88)
General description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACTN2 (P35609).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC
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Storage Class
10 - Combustible liquids
wgk
WGK 1
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