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Merck
CN

SAB5702654

Anti-Mesothelin Antibody, clone 5R9H8, Rabbit Monoclonal

Synonym(s):

MPF, SMRP

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5R9H8, monoclonal
Application:
IF, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

5R9H8, monoclonal

form

liquid

mol wt

48 kDa

species reactivity

rat, human

concentration

0.55 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

YFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLS

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MSLN(10232)

General description

This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Mesothelin (Q13421).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB5702654-100UL04065270692610