SAB5702655
[KO Validated]Anti-HDAC8 Antibody, clone 1O2Y5, Rabbit Monoclonal
Synonym(s):
CDA07, CDLS5, HD8, HDACL1, MRXS6, RPD3, WTS
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
IF, IHC, IP, WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
material
colorless
clone
1O2Y5, monoclonal
form
liquid
mol wt
42 kDa
species reactivity
human, rat
concentration
0.3 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGY
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HDAC8(55869)
General description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC8 (Q9BY41).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC, IF/ICC, IP
Storage Class
10 - Combustible liquids
wgk
WGK 1
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