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Merck
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SAB5702689

Anti-RNF40 Antibody, clone 8I7R5, Rabbit Monoclonal

Synonym(s):

BRE1B, RBP95, STARING

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
8I7R5, monoclonal
Application:
IHC, WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

8I7R5, monoclonal

form

liquid

mol wt

130 kDa

Quality Level

100

Gene Information

human ... RNF40(9810)

concentration

1.65 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

RELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAELEENQELANSRMAELEKLQAELQGAVRTNERLKVALRSLPEEVVRETGEYRMLQAQFSLLYNESLQVKTQLDEARGLLLATKNSHLRHIEHME

UniProt accession no.

O75150

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 231-431 of human RNF40 (O75150).

Application

WB, IHC

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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