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Merck
CN

SAB5702706

Anti-IKZF3 Antibody, clone 4U7F9, Rabbit Monoclonal

Synonym(s):

AIO, AIOLOS, ZNFN1A3

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human,
Conjugate:
unconjugated
Application:
IF, IHC, IP, WB
Citations:
-

Key Documents

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species reactivity

human,

biological source

rabbit

conjugate

unconjugated

material

colorless

clone

4U7F9, monoclonal

form

liquid

mol wt

65 kDa

concentration

0.5 mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

IYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRALLK

UniProt accession no.

Q9UKT9

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... IKZF3(22806)

General description

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 400-509 of human IKZF3 (Q9UKT9).

Application

WB, IHC, IF/ICC, IP

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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