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Merck
CN

SAB5702725

Anti-eIF2A Antibody, clone 8V8H7, Rabbit Monoclonal

Synonym(s):

CDA02, EIF-2A, MST089, MSTP004, MSTP089

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
8V8H7, monoclonal
Application:
immunohistochemistry
western blot
Species reactivity:
rat, rat, human
Citations:
Technique(s):
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
Uniprot accession no.:
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

8V8H7, monoclonal

form

liquid

mol wt

60 kDa

species reactivity

rat, rat, human

concentration

0.50 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

ALRNKPITNSKLHEEEPPQNMKPQSGNDKPLSKTALKNQRKHEAKKAAKQEARSDKSPDLAPTPAPQSTPRNTVSQSISGDPEIDKKIKNLKKKLKAIEQL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... EIF2A(83939)

Application

WB, IHC

General description

This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 450-550 of human eIF2A (Q9BY44).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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