SAB5702743
Anti-SKP1 Antibody, clone 10G5X5, Rabbit Monoclonal
Synonym(s):
EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
10G5X5, monoclonal
Application:
immunofluorescence
western blot
western blot
Species reactivity:
rat, rat, human
Citations:
Technique(s):
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
western blot: 1:500 - 1:2000
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
10G5X5, monoclonal
form
liquid
mol wt
20 kDa
species reactivity
rat, rat, human
concentration
0.25 mg/mL
technique(s)
immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
HHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKTPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SKP1(6500)
Application
WB, IF/ICC
General description
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 64-163 of human SKP1 (P63208).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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