SAB5702877
Anti-KDM4B/JMJD2B Antibody, clone 8I0I1, Rabbit Monoclonal
Synonym(s):
JMJD2B, TDRD14B
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
8I0I1, monoclonal
form
liquid
mol wt
150 kDa
species reactivity
human, rat, rat
concentration
1.5 mg/mL
technique(s)
ChIP: 1:50 - 1:200
immunofluorescence: 1:50 - 1:200
immunoprecipitation (IP): 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
PPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWN
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KDM4B(23030)
General description
Histone demethylase that specifically demethylates ′Lys-9′ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ′Lys-4′, H3 ′Lys-27′, H3 ′Lys-36′ nor H4 ′Lys-20′. Only able to demethylate trimethylated H3 ′Lys-9′, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KDM4B/JMJD2B (O94953).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IF/ICC, IP, ChIP
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Regulatory Information
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