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Merck
CN

SAB5702877

Anti-KDM4B/JMJD2B Antibody, clone 8I0I1, Rabbit Monoclonal

Synonym(s):

JMJD2B, TDRD14B

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
ChIP, IF, IP, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

8I0I1, monoclonal

form

liquid

mol wt

150 kDa

species reactivity

human, rat

concentration

1.5 mg/mL

technique(s)

ChIP: 1:50 - 1:200, immunofluorescence: 1:50 - 1:200, immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

PPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWN

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KDM4B(23030)

General description

Histone demethylase that specifically demethylates ′Lys-9′ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ′Lys-4′, H3 ′Lys-27′, H3 ′Lys-36′ nor H4 ′Lys-20′. Only able to demethylate trimethylated H3 ′Lys-9′, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KDM4B/JMJD2B (O94953).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC, IP, ChIP


Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

低风险生物材料
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Global Trade Item Number

SKUGTIN
SAB5702877-100UL04065270687340