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SAB5702946

Anti-CSNK2A2 Antibody, clone 3W5P4, Rabbit Monoclonal

Synonym(s):

CSNK2A2,CK2A2,CK2alpha,CSNK2A1

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
human, rat
Conjugate:
unconjugated
Application:
IP, WB
Citations:
-
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

material

colorless

clone

3W5P4, monoclonal

form

liquid

mol wt

43 kDa

species reactivity

human, rat

concentration

1 mg/mL

technique(s)

immunoprecipitation (IP): 1:50 - 1:200, western blot: 1:500 - 1:1000

color

colorless

isotype

IgG

immunogen sequence

LGTEELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKEQSQPCADNAVLSSGLTAAR

UniProt accession no.

P19784

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CSNK2A2(1459)

General description

Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating ′Ser-392′ of p53/TP53 following UV irradiation.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CSNK2A2 (NP_001887.1).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IP

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H317,H411

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

常规特殊物品

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Global Trade Item Number

SKUGTIN
SAB5702946-100UL04065270707727