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Merck
CN

SAB5702963

Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal

Synonym(s):

COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
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biological source

rabbit

conjugate

unconjugated

material

colorless

clone

2V7G8, monoclonal

form

liquid

mol wt

72 kDa

species reactivity

mouse, mouse

concentration

0.8 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

GETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PTGS2(5743)

Application

WB, IHC

General description

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 505-604 of human COX2/PTGS2 (P35354).
PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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