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Merck
CN

SAB5702986

Anti-Dystrophin Antibody

rabbit monoclonal, 10G10K7

Synonym(s):

BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
Clone:
10G10K7, monoclonal
Species reactivity:
mouse, rat
Application:
IF, IHC
Citations:
-

Key Documents

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Product Name

Anti-Dystrophin Antibody, clone 10G10K7, Rabbit Monoclonal,

biological source

rabbit

material

colorless

clone

10G10K7, monoclonal

form

liquid

species reactivity

mouse, rat

concentration

0.5mg/mL

technique(s)

immunofluorescence: 1:50 - 1:200, immunohistochemistry: 1:50 - 1:200

color

colorless

isotype

IgG

immunogen sequence

LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM

UniProt accession no.

P11532

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... DMD(1756)

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General description

This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

IHC, IF/ICC

Storage Class

10 - Combustible liquids

wgk

WGK 1

Regulatory Information

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