SAB5703012
Anti-TFPI Antibody, clone 5J8X8, Rabbit Monoclonal
Synonym(s):
EPI, LACI, TFI, TFPI1
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5J8X8, monoclonal
Application:
WB
Citations:
-
biological source
rabbit
Quality Level
conjugate
unconjugated
material
colorless
clone
5J8X8, monoclonal
form
liquid
mol wt
38 kDa
species reactivity
human
concentration
0.71 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
PQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIFVKNM
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TFPI(7035)
General description
This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
Immunogen
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 200-304 of human TFPI (P10646).
Application
WB
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SAB5703012-100UL | 04065270540256 |