Anti-Tbx3 Antibody, clone 3G9F1, Rabbit Monoclonal

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]

A synthetic peptide corresponding to a sequence within amino acids 644-743 of human Tbx3 (O15119).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

WB