SAB5703034
Anti-TIN2/TINF2 Antibody, clone 4W5P2, Rabbit Monoclonal
Synonym(s):
DKCA3, TIN2
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Species reactivity:
rat, human
Conjugate:
unconjugated
Application:
WB
Citations:
-
biological source
rabbit
Quality Segment
conjugate
unconjugated
material
colorless
clone
4W5P2, monoclonal
form
liquid
mol wt
45 kDa
species reactivity
rat, human
concentration
1.14 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
NLAEPMEQNPPQQQRLALHNPLPKAKPGTHLPQGPSSRTHPEPLAGRHFNLAPLGRRRVQSQWASTRGGHKERPTVMLFPFRNLGSPTQVISKPESKEEH
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TINF2(26277)
General description
This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010]
Immunogen
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 210-309 of human TIN2/TINF2 (Q9BSI4).
Application
WB
Storage Class
10 - Combustible liquids
wgk
WGK 1
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