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Merck
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SAB5703037

Anti-Phospho-BRD4(pSer1083) Antibody, clone 5B6X4, Rabbit Monoclonal

Synonym(s):

BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
5B6X4, monoclonal
Application:
WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

material

colorless

clone

5B6X4, monoclonal

form

liquid

mol wt

200 kDa

species reactivity

human

concentration

1mg/mL

technique(s)

western blot: 1:100 - 1:500

color

colorless

isotype

IgG

immunogen sequence

HQSPP

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BRD4(23476)

General description

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
A synthetic phosphorylated peptide around S1083 of human BRD4 (NP_490597.1).

Application

WB


pictograms

Exclamation markEnvironment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Chronic 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Information

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Global Trade Item Number

SKUGTIN
SAB5703037-100UL04065270712868