SAB5703045
Anti-CD38 Antibody, clone 1G3, Rabbit Monoclonal
Synonym(s):
CD38,ADPRC 1,ADPRC1
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About This Item
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
1G3, monoclonal
Application:
flow cytometry
Species reactivity:
human
Citations:
Technique(s):
flow cytometry: 1:50 - 1:200
Uniprot accession no.:
biological source
rabbit
conjugate
unconjugated
material
colorless
clone
1G3, monoclonal
form
liquid
species reactivity
human
concentration
1 mg/mL
technique(s)
flow cytometry: 1:50 - 1:200
color
colorless
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CD38(952)
Application
FC
General description
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5′-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
Immunogen
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human CD38.
Storage Class
10 - Combustible liquids
wgk
WGK 1
Regulatory Information
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