SAB6010046
Anti-phospho-EIF2S1 (S51) antibody, clone 1C6, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
1C6, recombinant monoclonal
Application:
ELISA, FACS, IF, IHC
Citations:
-
recombinant
expressed in HEK 293 F cells
Quality Segment
conjugate
unconjugated
antibody product type
primary antibodies
clone
1C6, recombinant monoclonal
form
liquid
mol wt
150 kDa
purified by
affinity chromatography
species reactivity
human
concentration
1.5mg/ml
technique(s)
ELISA: 2000:10000, flow cytometry: 1:50-1:200, immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200
isotype
IgG
UniProt accession no.
shipped in
wet ice
storage temp.
-10 to -25°C
target post-translational modification
phosphorylation (pSer51)
General description
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Immunogen
A synthesized peptide derived from human Phospho-EIF2S1 (S51)
Physical form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preparation Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Other Notes
28-68aa
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable