SAB6010046
Anti-phospho-EIF2S1 (S51) antibody, clone 1C6, Rabbit Monoclonal
recombinant, expressed in HEK293F cells
别名:
Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, EIF2S1, EIF2A
重组
expressed in HEK 293 F cells
质量水平
偶联物
unconjugated
抗体产品类型
primary antibodies
克隆
1C6, recombinant monoclonal
表单
liquid
分子量
150 kDa
纯化方式
affinity chromatography
种属反应性
human
浓度
1.5mg/ml
技术
ELISA: 2000:10000
flow cytometry: 1:50-1:200
immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
同位素/亚型
IgG
UniProt登记号
运输
wet ice
储存温度
-10 to -25°C
靶向翻译后修饰
phosphorylation (pSer51)
一般描述
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
免疫原
A synthesized peptide derived from human Phospho-EIF2S1 (S51)
外形
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
制备说明
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
其他说明
28-68aa
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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