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Merck
CN

SAB6012018

Anti CLPX Antibody, clone 23GB1745, Rabbit Monoclonal

newenhanced validation

clone 23GB1745, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

EPP2

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB1745, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

69 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

0.5 mg/ml

technique(s)

immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000166855

NCBI accession no.

NP_006651.2

UniProt accession no.

O76031

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CLPX(10845)

General description

The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 600-633 of human CLPX [NP_006651.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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