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Merck
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SAB6012044

Anti BRAT1 Antibody, clone 23GB4355, Rabbit Monoclonal

newenhanced validation

clone 23GB4355, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

BAAT1, C7ORF27, C7orf27, NEDCAS, RMFSL

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB4355, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

88 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

0.2 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000106009

NCBI accession no.

NP_689956.2

UniProt accession no.

Q6PJG6

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BRAT1(221927)

General description

The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 701-821 of human BRAT1 [NP_689956.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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