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SAB6012052

Anti MPP1 Antibody, clone 23GB4770, Rabbit Monoclonal

newenhanced validation

clone 23GB4770, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

AAG12, DXS552E, MRG1, PEMP

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB4770, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

52 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

0.25 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000130830

NCBI accession no.

NP_002427.1

UniProt accession no.

Q00013

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MPP1(4354)

General description

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 305-350 of human MPP1 [NP_002427.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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