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SAB6012074

Anti Frizzled class receptor 8 Antibody, clone 23GB5470, Rabbit Monoclonal

greener alternative

clone 23GB5470, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

FZ-8, HFz8

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About This Item

UNSPSC Code:
12352203

Key Documents

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Product Name

Anti Frizzled class receptor 8 Antibody, clone 23GB5470, Rabbit Monoclonal, clone 23GB5470, recombinant rabbit monoclonal, expressed in HEK293 cells

biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5470, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

73 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

100

Gene Information

human ... FZD8(8325)

sustainability

Greener Alternative Product

concentration

1 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000177283

NCBI accession no.

NP_114072.1

UniProt accession no.

Q9H461

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 640-694 of human Frizzled 8 [NP_114072.1].

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

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