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Merck
CN

SAB6012076

Anti GABBR2 Antibody, clone 23GB5500, Rabbit Monoclonal

newenhanced validation

clone 23GB5500, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

DEE59, GPR51, GPRC3B, NDPLHS

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5500, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

106 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

1.5 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000136928

NCBI accession no.

NP_005449.5

UniProt accession no.

O75899

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GABBR2(9568)

General description

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 900-941 of human GABA B Receptor 2 [NP_005449.5].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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