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Merck
CN

SAB6012079

Anti Growth differentiation factor 3 Antibody, clone 23GB5540, Rabbit Monoclonal

newenhanced validation

clone 23GB5540, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

GDF-3, KFS3, MCOP7

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5540, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

41 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

1.3 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000184344

NCBI accession no.

NP_065685.1

UniProt accession no.

Q9NR23

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GDF3(9573)

General description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 300-364 of human GDF3 [NP_065685.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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