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Merck
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SAB6012087

Anti Dual specificity phosphatase 1 Antibody, clone 23GB5760, Rabbit Monoclonal

newenhanced validation
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clone 23GB5760, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

HVH1, MKP-1, PTPN10

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5760, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

39 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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sustainability

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concentration

1.5 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000120129

NCBI accession no.

NP_004408.1

UniProt accession no.

P28562

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DUSP1(1843)

General description

The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 102-150 of human DUSP1 [NP_004408.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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