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Merck
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SAB6012096

Anti ERCC8 Antibody, clone 23GB5905, Rabbit Monoclonal

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clone 23GB5905, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

CKN1, CSA, UVSS2

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit (Monoclonal)

Quality Level

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5905, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

44 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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sustainability

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concentration

2.5 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

NCBI accession no.

UniProt accession no.

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shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ERCC8(1161)

General description

This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 351-396 of human ERCC8 [NP_000073.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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