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Merck
CN

SAB6012100

Anti HINT1 Antibody, clone 23GB5985, Rabbit Monoclonal

newenhanced validation
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clone 23GB5985, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

NMAN, PKCI-1, PKCI1

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5985, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

14 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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sustainability

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concentration

0.8 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000169567

NCBI accession no.

NP_005331.1

UniProt accession no.

P49773

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HINT1(3094)

General description

This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed. [provided by RefSeq, Dec 2015]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1-32 of human HINT1 [NP_005331.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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