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Merck
CN

SAB6012144

Anti Myosin VIIA Antibody, clone 24GB665, Rabbit Monoclonal

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clone 24GB665, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

DFNA11, MYU7A, NSRD2, USH1B

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
24GB665, recombinant monoclonal
Application:
FACS, IF, WB
Citations:
-
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biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB665, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

254 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

Gene Information

human ... MYO7A(4647)

sustainability

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concentration

2 mg/ml

technique(s)

flow cytometry: 1:2000, immunofluorescence: 1:100-:1000, western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

NCBI accession no.

UniProt accession no.

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shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 11-85 of human Myosin VIIa [NP_000251.3].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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