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Merck
CN

SAB6012162

Anti Reticulon 4 Antibody, clone 24GB1210, Rabbit Monoclonal

newenhanced validation

clone 24GB1210, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

ASY, NOGO, NSP-CL, RTN4-C

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB1210, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

130 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

1.5 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000115310

NCBI accession no.

NP_001308788.1

UniProt accession no.

Q9NQC3

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RTN4(57142)

General description

This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 115-160 of human Nogo [NP_001308788.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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