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SAB6012196

Anti UBA7 Antibody, clone 24GB2660, Rabbit Monoclonal

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clone 24GB2660, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

UBA1B, UBE1L, UBE2, UBE7

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
24GB2660, recombinant monoclonal
Application:
FACS, IF, WB
Citations:
-

Key Documents

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biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB2660, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

112 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

100

Gene Information

human ... UBA7(7318)

sustainability

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concentration

0.25 mg/ml

technique(s)

flow cytometry: 1:2000, immunofluorescence: 1:100-:1000, western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000182179

NCBI accession no.

NP_003326.2

UniProt accession no.

P41226

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Related Categories

General description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1-62 of human Ube1L / UBA7 [NP_003326.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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