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Merck
CN

SAB6012207

Anti UBA2 Antibody, clone 24GB2275, Rabbit Monoclonal

newenhanced validation

clone 24GB2275, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

ACCES, ARX, HRIHFB2115, SAE2, UBLE1B

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB2275, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

71 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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concentration

1.5 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000126261

NCBI accession no.

NP_005490.1

UniProt accession no.

Q9UBT2

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... UBA2(10054)

General description

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 50-100 of human SAE2 / UBA2 [NP_005490.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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