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Merck
CN

SAB6012224

Anti-phospho-CDK1/2/3(Thr14) Antibody, clone 23GB1430, Rabbit Monoclonal

newenhanced validation
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clone 23GB1430, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

CDC2, CDC28A, CDKN1

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB1430, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

34 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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sustainability

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concentration

0.8 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000170312

NCBI accession no.

NP_001777.1

UniProt accession no.

P06493

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CDK1(983)

Related Categories

General description

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2023]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 7-21 of human Phospho-CDK1/2/3 (T14) [NP_001777.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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