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Merck
CN

SAB6012256

Anti PDGFRA Antibody, clone 24GB1165, Rabbit Monoclonal

newenhanced validation
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clone 24GB1165, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

CD140a, GAS9, PDGFR-2, PDGFR2

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

24GB1165, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

123 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
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sustainability

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concentration

1 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000134853

NCBI accession no.

NP_001334758.1

UniProt accession no.

P16234

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PDGFRA(5156)

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General description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1050-1089 of human APDGFR alpha [NP_001334758.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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