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SAB6012300

KD-Validated Anti CSE1L Antibody, clone 23GB3515, Rabbit Monoclonal

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clone 23GB3515, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

CAS, CSE1, Exp2, XPO2

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About This Item

UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
23GB3515, recombinant monoclonal
Application:
FACS, IF, WB
Citations:
-

Key Documents

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biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB3515, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

110 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

100

Gene Information

human ... CSE1L(1434)

sustainability

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concentration

0.5 mg/ml

technique(s)

flow cytometry: 1:2000, immunofluorescence: 1:100-:1000, western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000124207

NCBI accession no.

NP_001307.2

UniProt accession no.

P55060

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Related Categories

General description

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 900-971 of human Exportin2 [NP_001307.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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