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Merck
CN

SAB6012321

KD-Validated Anti SEC24D Antibody, clone 23GB2510, Rabbit Monoclonal

newenhanced validation

clone 23GB2510, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

CLCRP2, KIAA0755

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit (Monoclonal)

Quality Level

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB2510, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

113 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

1.2 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SEC24D(9871)

General description

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 1-43 of human SEC24D [NP_055637.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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Regulatory Information

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