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Merck
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SAB6012360

KD-Validated Anti Katanin catalytic subunit A1 Antibody, clone 23GB4765, Rabbit Monoclonal

newenhanced validation

clone 23GB4765, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

N/A

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB4765, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

56 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

0.4 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000186625

NCBI accession no.

NP_001191005.1

UniProt accession no.

O75449

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... KATNA1(11104)

General description

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2011]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 465-491 of human p60 katanin [NP_001191005.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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