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Merck
CN

SAB6012361

KD-Validated Anti LMAN1 Antibody, clone 23GB4750, Rabbit Monoclonal

newenhanced validation

clone 23GB4750, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

ERGIC53, F5F8D, FMFD1, GP58, MCFD1

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB4750, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

58 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

2 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000074695

NCBI accession no.

NP_005561.1

UniProt accession no.

P49257

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... LMAN1(3998)

General description

The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 301-385 of human LMAN1 [NP_005561.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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