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Merck
CN

SAB6012373

KD-Validated Anti Aminopeptidase A / CD249 Antibody, clone 23GB5325, Rabbit Monoclonal

newenhanced validation

clone 23GB5325, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

AP-A, APA, CD249, EAP, Gp160

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5325, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

109 kDa

species reactivity

human, rat

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

1.5 mg/ml

technique(s)

western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000138792

NCBI accession no.

NP_001968.3

UniProt accession no.

Q07075

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ENPEP(2028)

General description

The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 900-957 of human Aminopeptidase A / CD249 [NP_001968.3].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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