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Merck
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SAB6012381

KD-Validated Anti HuR / ELAVL1 Antibody, clone 23GB5815, Rabbit Monoclonal

newenhanced validation

clone 23GB5815, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

HUA, HUR, MELG

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About This Item

UNSPSC Code:
12352203

Key Documents

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biological source

rabbit (Monoclonal)

Quality Level

100

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB5815, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

36 kDa

species reactivity

rat, human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

concentration

0.8 mg/ml

technique(s)

flow cytometry: 1:2000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000066044

NCBI accession no.

NP_001410.2

UniProt accession no.

Q15717

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ELAVL1(1994)

General description

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]

Immunogen

A synthesized peptide corresponding to a sequence within amino acids 52-96 of human HuR / ELAVL1 [NP_001410.2].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

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